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These drug classes have consistently demonstrated substantial benefits in slowing kidney function decline, reducing cardiovascular events, and improving clinical outcomes in people with type 2 diabetes mellitus

However, there is no clear correlation between autophagy activity and the abundance of autophagosomes or LC3B proteins (146, 149)

Clinical trials are currently underway to determine whether these drugs might slow progression of Alzheimers disease or Parkinsons disease

Most patients begin noticing reduced cravings and improved appetite control within 12 weeks, with visible weight-loss results typically appearing around 46 weeks

Int Immunopharmacol (2020) 82:106328