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Inspect the vial seal, check for visible moisture or discoloration, and confirm that the shipment was kept within the specified temperature range during transit

These findings are further supported by another sub-analysis of SURMOUNT1, which reported a 33.9% (8.2% for placebo) reduction in fat mass and a 10.9% (2.6% for placebo) reduction in lean mass by week 72, with approximately 75% of weight loss attributable to fat mass, consistent across clinically relevant subgroups [68]

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To consolidate these design-function relationships across biomedical contexts, Figure 7 provides a schematic overview of representative precursors and engineering strategies discussed in this section