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Specifically, the upregulation of ABCG2 expression and function in response to soluble uric acid in intestinal cell lines is dependent on PDZK1 at the transcriptional level

FLOW The Evaluate Renal Function With Semaglutide Once Weekly (FLOW) trial is the first dedicated kidney outcome study specifically designed to assess the effect of a GLP-1 receptor agonist (once-weekly subcutaneous semaglutide) in people with type 2 diabetes mellitus and CKD at high-risk of progression (Table 1, Fig

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