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1990 Jun 15;169(2):443-50

These coactivators generally orchestrate with DNA-bound transcription factors, such as nuclear respiratory factors (NRF1, NRF2), estrogen-related receptors (ERR, ERR, and ERR), and myocyte enhancer factor 2 (MEF2) to drive the expression of target genes

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TLR activation leads to enhanced transcription of pro-inflammatory cytokines such as TNF and interleukin-6 (IL-6)