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Its established molecular architecture and documented metal-binding properties have made it a valuable reference compound for studies examining ligand-metal interactions, metallopeptide pharmacology, structure-function relationships, and copper-dependent regulatory mechanisms.

Time-to-onset analysis revealed a median latency of 32 days (IQR 7122) for GLP-1 RA-related NAEs, with 45.28% occurring within 30 days of treatment initiation

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