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Psoriasis involves uncontrolled activation of T helper cells (Th1) and (Th17), resulting in the overproduction of pro-inflammatory cytokines, such as IL-1, IL-6, IL-23, IL-22, interferon alpha (IFN-), and TNF- (204206)
As of mid-2025, retatrutide is unlicensed in the UK
If your doctor believes these are inappropriate or insufficient for your condition, they can submit a step therapy exception request
Quick Answer: There is no established direct link between tirzepatide use and increased sun sensitivity, though patients should maintain standard sun protection practices during treatment
Need for further research Despite the promising results, the authors remain cautious
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