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Both groups showed similar improvements in HbA1c and insulin sensitivity, but the pioglitazone group additionally showed increased levels of mitochondrial gene expression and AMPK phosphorylation [124]

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Cells found in the lining of the small intestine (called L-cells) are the primary source of glucagon-like peptide 1, although the pancreas and the central nervous system both secrete it, albeit in lower amounts

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