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This pathway allowed AOD-9604 to be marketed in the United States as a dietary supplement without the efficacy evidence required for a New Drug Application (NDA)

| Target Concentration | BAC Water to Add | Dose per 10 units on syringe | |---------------------|-----------------|------------------------------| | 8mg/ml | 3.0ml | 0.8mg | | 12mg/ml | 2.0ml | 1.2mg | | 6mg/ml | 4.0ml | 0.6mg | **Best for:** Patients on 4-8mg weekly doses (therapeutic range)

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This slow-drip method prevents the powder from foaming, which can damage the delicate peptide structure

Interactions between foods and oral or injectable forms of methylcobalamin are not expected