where was glp 1 discovered Reflections on the discovery GLP-1 as a satiety hormone: Implications for obesity therapy and future directions The Minds Behind GLP-1: A

Stahl EP, Dhindsa DS, Lee SK, Sandesara PB, Chalasani NP, Sperling LS (2019) Nonalcoholic fatty liver disease and the heart: JACC state-of-the-art review

After 48 weeks of treatment, participants receiving 8 mg and 12 mg doses experienced a mean body weight reduction of 22.8% and 24.2%, respectivelyan outcome comparable to bariatric surgery

Carbohydrate strategy: Do not eliminate carbs

You do not need to memorize a speech, but you do need to remember three things: your specific health goals (not "lose weight" but "reduce my A1c from 6.1 to below 5.7 and lose enough weight to reduce my blood pressure medication"), the treatments you have already tried, and your awareness of GLP-1 side effects and commitment to managing them

At steady state, the difference between injecting on day six versus day seven is smaller in absolute terms than during the initial titration phase