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The most interesting point of this study is the preventive effect of this approach due to a persistence of efficiency during the time after a single injection of the treatment 53

Since the helix D1 constituted a part of the entrance to the ligand-binding pocket, it is suggested that the orientation of helix D1 affected the size of the ligand-binding pockets, and thus the helix D1 might be an important structural determinant for the ligand- binding specificity

This combination amplifies the natural nocturnal GH surge through two distinct receptor systems, producing more GH release than either peptide alone

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