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TJ complexes are primarily composed of transmembrane proteins including occludins, junctional adhesion molecules, and claudin family members that function collectively to form pores with selective permeability to ions and molecules (Brenchley and Douek 2012

PubMed 33035815

Molecules, 27 (21), 7167

2 Morehouse School of Medicine, Department of Microbiology, Biochemistry and Immunology, Atlanta, GA, USA Abstract: A cure for sickle cell anemia (SCA) is not available to all who have inherited this devastating genetically inherited disease

There's no strong research that shows that microdosing works well, and it isn't approved by the FDA, which means the agency hasn't reviewed it for safety