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In a mouse model of colorectal cancer, oral administration of PEITC reduced both the number and size of polyps

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HUVECs: Human umbilical vein endothelial cells ICAM-1: Intercellular adhesion molecule 1 IFN-: Interferon gamma IL: Interleukin JNK: C-Jun N-terminal kinase LAB: Lactic acid bacteria LDL: Low-density lipoprotein MAPK: Mitogen-activated protein kinase MBC: Minimum bactericidal concentration MCP-1: Monocyte chemoattractant protein-1 MIC: Minimum inhibitory concentration NAFLD: Non-alcoholic fatty liver disease NF-b: Nuclear factor kappa B NO: Nitric oxide ox-LDL: Oxidized low-density lipoprotein PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses ROS: Reactive oxygen species SHR: Spontaneously hypertensive rats TNF-: Tumour necrosis factor alpha VCAM-1: Vascular cell adhesion molecule 1 References AbMajid, N

Due to the wide spectrum of signaling cascades, crosstalk, and complex molecular mechanisms involved in the progression of insulin resistance (IR), it is critical to gain a deeper understanding of the mechanistic insights to uncover novel, comprehensive therapeutic strategies to prevent and manage this multifaceted condition