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And these drugs carry their own side effect profile nausea, gastrointestinal issues, and in rare cases more serious complications that need to be weighed carefully

3.6 Stroke and post-stroke cognitive impairment (PSCI) Post-stroke patients show gut dysbiosis with reduced microbial diversity, increased pro-inflammatory bacteria, and decreased levels of SCFA-producing bacteria such as Faecalibacterium (Yin et al., 2015)

For example, recent work on SGLT2 inhibitors suggests potential effects on telomere biology

The prices might seem good, but anytime patients try to increase the dose, they increase the price

Overall, our results in mice highlight the limitations of using mouse models to study tirzepatide, requiring careful experimental design and interpretation of data in this species