Additionally, IMO can cause nutrient malabsorption, which further disrupts gut function and contributes to digestive symptoms like constipation
That is the core therapeutic mechanism behind appetite suppression and weight loss, but it also creates a side effect: food sits in the stomach longer, and sulfur-containing amino acids (cysteine and methionine) have more time to undergo bacterial fermentation, producing hydrogen sulfide gas
BPC-157's pro-angiogenic effects (promoting new blood vessel formation) could theoretically improve gastric tissue perfusion and support healing
At screening, the mean duration of diabetes was approximately 12 years, the mean BMI was approximately 31 kg/m2, mean eGFR was 80.6 mL/min/1.73 m2 and 86.1% of patients had an eGFR 60 mL/min
One study found that a year after stopping treatment, participants gained about 67% of the weight back