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Some people report a subtle feeling of fullness earlier in meals, while others experience mild nausea that typically resolves within a few days as your body adjusts

References include Jastreboff et al., New England Journal of Medicine , 2022 (SURMOUNT-1, tirzepatide for obesity), the FDA Zepbound prescribing information, the FDA Drug Shortages list (accessed Q1 2026), Patel et al., Annals of Pharmacotherapy , 2024 (compounded GLP-1 dosing errors), and the U.S

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However, it must be approached thoughtfully, under proper medical supervision, and with a clear understanding of both the potential benefits and limitations

Compounded versions are not FDA-approved and have not undergone clinical trials