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In a 2023 study [57], PD was induced in mice via MPTP administration, followed by eight weeks of KD feeding

As an aside, in a randomized, double-blind, placebo-controlled study, the addition of STS (80 mg/day, IV for 2 days before and 3 days after PCI) to the standard treatments could alleviate myocardial injury and the occurrence of short-term cardiovascular events in patients with non-ST elevation acute coronary receiving PCI [156]

Such nitration-dysfunction is specific to HGF among other major growth factors examined (FGF2, IGF1, and TGF-2), highlighting the inhibitory impact of accumulation of nitrated HGF on myogenic stem cell biology during aging 32

This ROS production, linked to mitochondrial respiratory chain dysfunction, leads to oxidative damage of critical cellular components including membranes, mitochondria, proteins, and DNA (Mesa-Arango et al., 2014

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