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Efficacy and safety of once-weekly tirzepatide for weight management compared to placebo: an updated systematic review and meta-analysis including the latest SURMOUNT-2 trial

IGF-1 LR3: Closely tied to muscle building, strength improvements, and lean tissue development

While weight loss might lead to reduced health care costs (estimates suggest a reduction of around $250 billion), the current prices of the medications mean that the math doesnt quite add up for insurance companies

For people who are curious about GLP-1s but hesitant about the cost , side effects, or intensity of a traditional program, GLP-1 microdosing could be a pretty sweet middle ground

One more clinical note: the trial used a gradual titration protocol specifically to manage tolerability