Some researchers prefer this because the slightly lower concentration gives them more precision, especially if they are doing half-step escalations like 6mg or 10mg between the standard protocol doses
J.JavadovS
In human beings, HOTYR absorption was higher when subjects ingested virgin olive oil than in refined oil (phenol-free) enriched with phenolic compounds, or when HOTYR was incorporated into a yogurt as functional food, with urinary recoveries of 44, 23, and 5.8%, respectively ( O -glucuronide conjugated HOTYR showed higher activity as a radical scavenger than its corresponding free form ( O -Gluc-HOTYR and 4- O -Gluc-HOTYR, did not show radical scavenging activity and capacity to protect low-density lipoproteins (LDL) against oxidation compare to HOTYR
The margin between proper storage and complete product failure is narrower than most protocols acknowledge
Moreover, multiple in vitro (64,65) and in vivo (66,67) studies suggest that ergothioneine activates the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2), which triggers the cellular antioxidant defence system
