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These patients reduced their initial weight by 5% through a low-calorie diet during the 4-12 weeks pre-trial induction period

Modulates the immune system in a multiple sclerosis mouse model

The Ruta graveolens therapeutic role, an evergreen shrub with a characteristic smell, instead, in the pathological condition of MS, may be linked to its inflammatory and antioxidant properties, in association with the ability to inhibit potassium channels of isolated axons (Bohuslavizki et al., 1992)

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HDI combinations with cytotoxic chemotherapy In an attempt to find a niche for HDIs, they have been tested in combination with a variety of conventional cytotoxic chemotherapeutic agents