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These introduce cavitation bubbles and turbulent flow that denature proteins

Interestingly, SIRT1 inhibition subsequently affects the phosphorylation of AMPK, leading to downstream activation of acetyl-CoA carboxylase, promotes the synthesis of polyunsaturated fatty acids, which serve as substrates for lipid peroxidation and ferroptosis induction (Zhang et al., 2023a)

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Cell 173 , 11231134.e11 (2018)

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