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GIP is another naturally occurring metabolic hormone that works hand-in-hand with GLP-1 to manage how our bodies process and store energy

These NFTs accumulate inside neurons and interfere with intracellular transport, leading to impaired cell function and neuronal death (Macdonald et al., 2019)

For instance, tirzepatide, sold under the brand name Zepbound, binds to both GLP-1 and GIP receptors

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Advanced formulations use technologies such as liposomal encapsulation, nanoparticles, or sustained-release systems to improve skin bioavailability