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Additionally, RcGPX4 depended on the MAPK3-ICE1-C-repeat-binding factor (CBF)-COR signal transduction pathway and ABA-dependent pathway to negatively regulate the freezing tolerance of transgenic plants

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It has been reported that SIRT1 promotes autophagy process via stimulation expression of tuberous sclerosis 2 proteins and FOXO1 which increase the survival of neuronal tissues (Obrador et al

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