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An examination using murine models of coronary artery tying appeared to exhibit results which implied that TB-500 might elevate integrin-associated kinase (ILK) and protein kinase B operations in the heart, possibly boosting early cardiomyocyte endurance and seemingly enhancing heart performance.(15)The experts also suggested that TB-500 might support the movement of myocardial and endothelial cells in the fetal heart and maintains this capability in mature cardiomyocytes

Namely, eNOS, iNOS and COX2 activity are thought to be specifically up-regulated in myocardial infarction [38]

But by normalizing the cytokine environment and supporting proper T-cell differentiation, it may create conditions more favorable for tolerance induction

Respiratory Medicine, 109, 1089-1104.Custovic, A., Simpson, A., & Woodcock, A

PubMed Fanidi A, Carreras-Torres R, Larose TL, et al