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Oxidative stress and endothelial dysfunction are consistently observed in hypertensive subjects, but emerging evidence suggests that they also have a causal role in the molecular processes leading to hypertension

4 This is the same vagal circuit that Samsoms pramlintide study implicated: the gastric-emptying delay is a brain-to-stomach command relayed down the vagus, not a peptide throttling the pylorus directly

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J Invertebr Pathol 130:154164

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