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Additionally, questions exist about potential effects in this population, including the impact of rapid weight loss on skin elasticity and lymphatic function in areas already affected by tissue changes

GLP-1 receptor agonists show improved glycemic control by enhancing insulin secretion and inhibiting glucagon secretion dependent on plasma glucose concentrations while minimizing hypoglycemia risk, reducing appetite, improving body weight, slowing gastric motility and reduce indirectly peripheral insulin resistance [7]

Another major question that remains unanswered as yet is that whether switching the normal machinery from eumelanin (which is protective against UV radiation) to pheomelanin (which photosensitizes UV-induced deoxyribonucleic acid damage as observed in cultured human melanocytes) by an external agent for long duration would result in an increased incidence of skin cancers

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