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Yes, the dosage and frequency of B12 injections are highly dependent on the severity of the deficiency and the presence of neurological symptoms

While levels above 700 pg/mL dont appear harmful, they also havent demonstrated additional performance benefits in research settings

The two are documented differently: the 10 mg vial at 600 mcg per dose (about 16 doses), the 20 mg vial at 250 mcg per dose (about 80 doses)

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corroborated by Oostdyk 2024) and downregulates surface GLP-1R within 12 hours at physiological albumin (Hinds 2024), so the sustained signal held against that fade, set by dose, is what carries the effect