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Real-world treatment patterns of glucose-lowering agents among patients with type 2 diabetes mellitus and cardiovascular disease or at risk for cardiovascular disease: an observational, cross-sectional

showed that blocking CD44 inhibited glioma cell proliferation by regulating autophagy (67) and this means GCH1 could induce glioma cell ferroptosis and influence immunity by autophagy

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337 Although all cell types responded to this inhibitor in vitro and showed promising therapeutic effects in vivo, 337 phase I clinical trials for treating advanced solid tumors ultimately failed due to cardiovascular toxicity and wide variability in patient responses