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Furthermore , applications include: Muscle Research: Protein synthesis (mTOR pathway), satellite cell activation, myosin heavy chain expression, and myofibrillar formation Metabolic Studies: Glucose metabolism, insulin sensitivity, lipolysis in adipose tissue, hepatic glucose output, and energy expenditure Model Systems: Myocyte cultures (C2C12, primary cells), adipocyte differentiation models, whole-animal metabolic chambers, and body composition analysis (DEXA, MRI) Musculoskeletal and Orthopedic Research Ipamorelin enables investigation of GH axis roles in tissue regeneration

Data synthesis We conducted meta-analyses when at least two studies reported relevant outcome data

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