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10.1016/j.isci.2021.102304 IScience 52 MehtarS.WiidI.TodorovS

Delaying treatment to await cheaper options may extend years of metabolic risk, missed cardiovascular benefits, and continued weight-related complications

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The injection can be given with or without food, providing additional flexibility

Hypotheses proposed to explain these abnormal discharges include increased spontaneous firing rates, enhanced synchrony of neuronal activity, and atypical excitatory patterns