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It also promotes angiogenesis (the formation of new blood vessels) and enhances the activity of fibroblasts, the cells that help heal wounds and repair tissue

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Resveratrol attenuates the anticancer efficacy of paclitaxel in human breast cancer cells in vitro and in vivo

High levels of leptin activate the long form of leptin receptors (Ob-Rb) on ECs, SMCs, and macrophages, initiating signaling pathways like janus kinase/signal transducer and activator of transcription (JAK/STAT) and mitogen-activated protein kinase (MAPK), which contribute to inflammation and vascular damage