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The article notes that airline cabin conditions typically stay cool enough for a GLP-1 medication, while checked baggage is subject to temperature swings that can move outside safe ranges

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There is also a need to determine whether these results translate to humans

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In humans, a RCT enrolling 156 patients with a BMI 27 kg/m 2 failed to demonstrate that one year of liraglutide treatment could improve pain in patients with KOA compared to placebo, despite a significant BW difference of approximately 4 kg at end of study 105

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