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Tirzepatide is a newer synthetic peptide that binds two incretin receptors at once: GLP-1 and GIP (glucose-dependent insulinotropic polypeptide)

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The single-molecule architecture allows precisely tuned biased signaling at each receptor, controlling the ratio of cAMP generation to beta-arrestin recruitment in ways that a two-drug combination cannot replicate at matched plasma concentrations

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While, when we hear about eating disorders, most people think of anorexia or bulimia, BED is actually far more common, affecting over 17 million people globally