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Most meaningful BMI changes occur when treatment lasts at least 1216 weeks, with the most significant improvements seen over 612 months

Several studies have shown that SDH-deficient cells exhibit increased tumorigenesis and that this increase is reversed by the addition of -KG, supporting the idea that succinate accumulation contributes to tumorigenesis through epigenetic modification 100

Eur J Pharmacol 451(2):119124 Shi C, Ma Y, Tian L, Li J, Qiao G, Liu C, Cao W, Liang C (2022) Verbascoside: an efficient and safe natural antibacterial adjuvant for preventing bacterial contamination of fresh meat