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Additionally, it has been shown to mitigate the adverse effects of corticosteroids on tendon-to-bone healing [12]

HO-1 has a high concentration in the spleen and is responsible for hemes quick elimination from circulation

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Fresh liver and eppididymal fat were removed, weighted, fixed in 4% formaldehyde (Elabscience, China) in a 1.5 ml Eppendorf tube (NEST Biotechnology, China) or snap-frozen in liquid nitrogen and stored at 80C for further research