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J Pediatr Gastroenterol Nutr 1986

doi: 10.3389/fimmu.2023.1290885 118 KolbrinkBvon Samson-HimmelstjernaFAMurphyJMKrautwaldS

We anticipate that sirtuins selectivity toward hydroxylated acyl groups can be addressed by identifying a method to synthesize the nucleosomes furnishing such acyl groups

The new research, published on-line in the journal Clinical Nutrition, divided 60 male albino Wistar rats into 10 groups, depending on age (young, middle-aged, or old) and supplementation with placebo (saline solution), L-carnitine only (300 mg per kg body weight per day), alpha-lipoic acid (100 mg per kg body weight per day), or both

It showed 41.7 mm WOMAC pain reduction versus 27.5 mm on placebo over 68 weeks