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Code availability All the statistical analyses in this study including propensity-score matching and KaplanMeier Survival analyses were conducted within the TriNetX platform by using its built-in functions

Most people experience hunger returning within 37 days of their last injection, even though semaglutide remains chemically detectable for 34 weeks

In this case, Zepbound mimics two hormones: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)

The body uses these pathways to regulate hunger, fullness, energy utilisation, and blood sugar control

Furthermore, peptides are involved in the regulation of nerve functions and can modulate the activity of digestive enzymes in the intestinal tract, thereby modulating nutrient absorption [6]