Two things can shift your thyroid needs during weight loss: Absorption variability (especially early on with dose increases) BNF Body weight changes (thyroid replacement dose requirements can change as weight changes) A practical approach many clinicians use is: Check TSH ( free T4) about 68 weeks after : starting tirzepatide, or a significant dose escalation, or a big, sustained drop in weight NICE also flags that because tirzepatide delays gastric emptying, some oral medicines (particularly those with a narrow therapeutic index) may need monitoring during escalation
Council on Clinical Cardiology
"One of my main concerns is that they're long-term adverse events for which we really don't have much data, especially for those who are taking them just for weight loss and not for diabetes." Ozempic, a weekly injectable that comes in a pre-filled, multi-dose disposable pen, has been associated with an increased risk of gallbladder disease and pancreatitis
As the main treatment goal is to prevent the progression of CKD, the ultimate end point of clinical trials in patients with lupus nephritis is currently assessed by the annual slope of eGFR or the number of patients reaching a distinct loss of eGFR during the treatment period 44,45
Follow-up Appointments : Attend scheduled follow-up appointments with your surgeon to monitor your progress and address any concerns