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IGF-1 activates intracellular pathways including PI3K/Akt and mTOR, which regulate protein synthesis and cellular growth

According to the subcellular localization of GSH1, the GSH synthesis initiates in the plastids, but the predominant transcript, especially in the case of multiple GSH2 transcript populations, encodes a cytosolic GSH2, suggesting the second step occurs in the cytosol (Otulak-Kozie et al., 2023)

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Quantitative trait loci mapping of circulating metabolites in cerebrospinal fluid to uncover biological mechanisms involved in brain-related phenotypes