More recently, the LixiPark trial (2023), a double-blind, randomized, placebo-controlled trial, used daily subcutaneous lixisenatide, another GLP-1 RA in 156 patients with early PD
Lancet Diabetes Endocrinol 6(11):859869 Mann JFE, rsted DD, Brown-Frandsen K, Marso SP, Poulter NR, Rasmussen S et al (2017) Liraglutide and renal outcomes in type 2 diabetes
Potential off-target effects: broad changes to methylation could, in theory, affect gene expression in ways not yet characterised
It builds custom meal plans, tracks your food using the BITES system, and even gives you recipes to keep things fun
Its just a matter of what the number is, not whether or not its going to impact research and development