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We applied these proportions to the most recent (2023) mid-year population estimates for Great Britain [39] to approximate the number of adults using these medications in 2024 and the number who would be interested in using them in the next year

Am J Gastroenterol 101(10):23792400

Metformin is also known to inhibit intestinal bile acid absorption [11] and modulate the composition of the gut microbiota [38], although neither is likely to be of relevance to the observations in the present study as glucose is a weak stimulus for gallbladder emptying and the current study was only conducted in an acute setting