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When applied to skin, it converts to retinaldehyde and then to retinoic acid, the active form

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Additionally, these mice exhibited reduced MMP and increased ROS levels in their oocytes, indicating mitochondrial dysfunction and oxidative stress imbalance

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Recent solution NMR structural investigations provide molecular models of p53 transactivation domain interactions with both FOXO4 and senolytic peptides, enabling rational design approaches for next-generation compounds