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The GLP-1 component suppresses appetite and slows gastric emptying, while the glucagon component is intended to increase energy expenditure and support fat metabolism in the liver

When collagen breaks down faster than your body can rebuild it, you start to see itin your face, your joints, and your skin

For retatrutide, supplementation must be handled separately since no commercially compounded formulations exist

To note, with the G-agonists, GIP receptors in the brain may respond differently than those peripherally, with less GI side effects

The FDAs prior warnings regarding the potential elevated risk of medullary thyroid carcinoma associated with GLP-1 RAs may encourage more patients on GLP-1 RA therapy to undergo thyroid ultrasounds, thereby enhancing tumor detection