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Abbreviations CNRC: Childrens Nutrition Research Center FFM: Fat-free mass GIP: Gastric inhibitory polypeptide GLP-1: Glucagon-like peptide-1 GPR: Glucose production rate HISI: Hepatic insulin sensitivity index IGI: Insulinogenic index iGLP-1: Intact GLP-1 MIGHTY: Metformin Influences Gut Hormones in Youth NGT: Normal glucose tolerance NIH: National Institutes of Health PYY: Peptide YY R a : Rate of appearance WBISI: Whole-body insulin sensitivity index References Zeitler P, Hirst K, Pyle L et al (2012) A clinical trial to maintain glycemic control in youth with type 2 diabetes

Lancet 387 (10026), 13771396

Intermittent fasting can help some people control calories, but it's often a poor fit when appetite is already heavily suppressed

Most patients notice appetite reduction between days 714 after their first injection

Yes, Alan Meds offers both medications and allows flexibility to switch between them if one is not effective or well-tolerated, based on your doctor's recommendation