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(2024) J Expo Sci Environ Epidemiol, 34: 3., and per- and poly-fluoroalkyl substances (PFAS), a group of endocrine-disrupting chemicals (EDCs) that have been shown to increase the risk of certain cancers, such as thyroid, ovarian, and breast cancers (see Sidebar 22 ) (318)van Gerwen M, et al

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The hormone then acts on multiple target tissues: it stimulates insulin secretion from pancreatic beta cells in a glucose-dependent manner, suppresses glucagon release from alpha cells, slows gastric emptying , and promotes satiety through central nervous system pathways

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Bupropion can raise blood pressure slightly, particularly in patients with pre-existing hypertension