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The vitrification process leads to mitochondrial dysfunction, characterized by a reduction in mitochondrial membrane potential (MMP), an increase in ROS, and elevated mitochondrial Ca 2+ levels (44), ultimately resulting in oocyte apoptosis and diminished developmental potential (45)

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Research applications Research applications In vitro GHRH receptor and GHSR (ghrelin receptor) binding and signaling assays cAMP/PKA pathway and somatotroph activation studies Cellular secretion and endocrine axis modeling Mechanistic combination and dose-response interaction studies For laboratory research use only

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