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Additionally, GSTP1 -transfected HepG2 cells were significantly more resistant against the cytotoxicity of both QIs under GSH-depleted conditions ( Figure 3 )

Nat Rev Gastroenterol Hepatol (2020) 17(11):687701

coli , and cells lacking both DsbA and endogenous glutathione can neither fully utilize the oxidative power of exogenous GSSG nor compensate the reductive power of GSH in their periplasm