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The medications currently under investigation include Ozempic, Wegovy, Rybelsus (all semaglutide), Trulicity (dulaglutide), Saxenda, and Victoza (both liraglutide), as well as Mounjaro and Zepbound (both tirzepatide)

Orforglipron, Eli Lillys oral non-peptide GLP-1 agonist currently awaiting approval, is synthesized by conventional organic chemistry in a standard chemical reactor

In other words, defects in any of the mechanisms involved can lead to a metabolic imbalance that leads to the pathogenesis of T2DM

Refined carbohydrates cause rapid insulin spikes followed by crashesexactly the pattern that drives overeating