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doi: 10.1016/j.jdiacomp.2016.08.018

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Third, although existing studies consistently demonstrate beneficial effects on hepatic steatosis and inflammation, the lack of head-to-head mechanistic and biomarker-based comparisons restricts the ability to distinguish between different GLP-1RAs or combination therapies in terms of their molecular pathways, immunemetabolic regulatory efficiency, and predictive biomarkers of therapeutic response

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Ethics statement The studies involving human participants were reviewed and approved by Institutional Review Board at Nova Southeastern University in Fort Lauderdale, FL, USA