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The numbers were small but highly significant [27]

Key points: Leverage platform data from similar biologics Eliminate redundant toxicology studies Combine endpoints within the same study Use in vitro and computational models earlier Align with the 3Rs principle (Replacement, Reduction, Refinement) Important step toward more ethical and efficient ocular drug development

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12 Nuts and Seeds: Almonds, walnuts, chia seeds, flax seeds (provide protein but are also calorie-dense, so portion control is key)

These diseases may affect more people in todays aging society