retatrutide vs. tirzepatide vs Tirzepatide: 28.7% vs 22.5% (2026) Retatrutide vs Tirzepatide Key Differences|

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Another small trial in obese hypogonadal men compared liraglutide vs testosterone gel over 16 weeks: the liraglutide group lost ~6% body weight and showed rising LH/FSH and SHBG (as mentioned earlier), whereas the testosterone therapy group gained lean mass but lost some endogenous gonadal function

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However, rapid or extensive weight loss may potentially worsen cellulite appearance in some individuals due to decreased skin elasticity and increased skin laxity

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